Estradiol

estradiol

Estradiol: The Essence of a Woman

Some would say that it’s the hormone that makes a girl an enemy of all men – if her monthly period is on. However, it’s the reverse that is true.

Estradiol is the hormone present in high levels during pregnancy. It is produced from developing ovarian follicles. Moreover, it is also important in the development of a woman's sexual characteristics sexual functioning, and even behavior. Hence, it is the hormone responsible for a woman’s attractiveness - some studies would even say that it’s one of the reasons why women spend so much money to make themselves beautiful.

There is also evidence that demonstrates its essential function for improved cognitive functioning, memory, and a woman's good night's sleep. When estradiol levels drop, a woman experiences behavioral problems such as depression and panic attacks. An optimal hormonal balance between progesterone and estradiol is therefore important to cancel out these effects.

What does Estradiol look like in Chemistry?

estradiol molecular structure

Let’s Get Building!

Using your Student Molecular Set from Duluth Labs let’s create Estradiol! You’ll need:

  • 18 Carbon Atoms

  • 2 Oxygen atoms

  • 24 Hydrogen atoms

  • 24 Small connectors (compact small bonds for hydrogen)

  • 20 Medium Connectors

  • 6 Long connectors

  • Molecular Tool (for Disassembly)

Put aside all the atoms and connectors needed.

Let’s Start Building With Our Ring A Portion!

Note: We will begin with building Ring A of estradiol molecule, starting at Carbon 1. We will build this portion of the molecule in a counterclockwise direction.

estradiol molecular structure

Let’s start!

Steps:

  • 1
    estradiol molecular structure

    1.Get one carbon atom (Carbon 1) then attach one carbon (Carbon 2) on its left using a medium connector. Then, add 1 hydrogen atom to each carbon using short connectors.

  • 2
    estradiol molecular model

    2.Attach another carbon (Carbon 3) atom below Carbon 2 using 2 long connectors.

  • 3
    estradiol molecular model

    3.Then, get an oxygen atom and attach this to Carbon 3 using 1 medium connector. Place a hydrogen atom on this oxygen using 1 small connector.

  • 4
    estradiol molecular model

    4.Get another carbon atom (Carbon 4) then attach this to Carbon 3 using 1 medium connector. Add one hydrogen atom to carbon 4 using 1 small connector.

  • 5
    estradiol molecular model

    5.Attach one carbon (Carbon 5) atom to Carbon 4 using 2 long connectors. Get another carbon (Carbon 10) then attach this above Carbon 5 using 1 medium connector.

  • 6
    estradiol molecular model

    6.Join Carbon 1 and Carbon 10 together using a 2 long connectors.

  • estradiol molecular model

    Yay! We've just built our Ring A Portion!

Note: We will now proceed with building Ring B of the estradiol molecule, starting with Carbon 9. We will build this portion of our molecule in a clockwise direction.

estradiol molecular structure

Let’s continue building!

Steps:

  • 1
    estradiol molecular model

    1.Attach one carbon atom (Carbon 9) to Carbon 10 (of Ring A) using a medium connector. Place one hydrogen atom on Carbon 9 using a small connector.

  • 2
    estradiol molecular model

    2.Get another Carbon atom (Carbon 8) then attach this to Carbon 9 using a medium connector. Then, add a hydrogen atom to Carbon 8 using a small connector.

  • 3
    estradiol molecular model

    3.Attach another carbon (Carbon 7) atom below Carbon 8 using a medium connector. Then, place two hydrogen atoms on carbon 7 using 2 small connectors.

  • 4
    estradiol molecular model

    4.Get another carbon atom (Carbon 6) and attach this to Carbon 7 using a medium connector. Place 2 hydrogen atoms on Carbon 6 using 2 small connectors.

  • 5
    estradiol molecular model

    5.Join Carbon 6 (of Ring B) and Carbon 5 (of Ring A) together using a medium connector

  • 6
    estradiol molecular model

    Hooray! We've just built our Ring B Portion!

Note: We will now proceed with building Ring C of the estradiol molecule, starting with Carbon 11. Likewise, we will proceed with building this portion in a clockwise direction.

estradiol molecular structure

Let’s continue building!

Steps:

  • 1
    estradiol molecular model

    1.Attach one carbon atom (Carbon 11) above Carbon 9 using a medium connector. Then, add 2 hydrogen atoms to Carbon 11 using 2 small connectors.

  • 2
    estradiol molecular model

    2.Connect another carbon atom (Carbon 12) to Carbon 11 using a medium connector. Likewise, add 2 hydrogen atoms to Carbon 12 using 2 small connectors.

  • 3
    estradiol molecular model

    3.Get another Carbon (Carbon 13) then attach this to Carbon 12 using a medium connector.

  • 4
    estradiol molecular model

    4.Get another carbon atom (Carbon 18) then attach this above Carbon 13 using 1 medium connector. Add 3 hydrogen atoms to Carbon 18 using 3 small connectors.

  • 5
    estradiol molecular model

    5.Get another carbon atom (Carbon 14) then have this attached below Carbon 13 using 1 medium connector. Then, add a hydrogen atom below Carbon 14 using a small connector.

  • 6
    estradiol molecular model

    6.Join Carbon 14 (of Ring C) and Carbon 8 (of Ring B) together using a medium connector.

  • estradiol molecular model

    Hooray! We've just built our Ring C Portion! We’re close to building our Estradiol molecule.

Note: We will now proceed with building Ring D of the estradiol molecule, starting with Carbon 17.

estradiol molecular structure

Let’s continue building!

Steps:

  • 1
    estradiol molecular model

    1.Get one carbon atom (Carbon 17) then attach this to Carbon 13 (of Ring C) using one medium connector. Add 1 hydrogen atom to Carbon 17 using a small connector.

  • 2
    estradiol molecular model

    2.Then, get one oxygen atom then attach this to Carbon 17 using one medium connector. Add a hydrogen atom to this oxygen using a small connector.

  • 3
    estradiol molecular model

    3.Get another carbon atom (Carbon 16) then attach this to Carbon 17 using a medium connector. Likewise, add 2 hydrogen atoms to Carbon 16 using two small connectors.

  • 4
    estradiol molecular model

    4.Attach one carbon atom (Carbon 15) below Carbon 16 using a medium connector. Place 2 hydrogen atoms to Carbon 15 using 2 small connectors.

  • 5
    estradiol molecular model

    5.Join Carbon 15 (of Ring D) and Carbon 14 (of Ring C) together using 1 medium connector.

Great work! Now we have our newly-built Estradiol molecule.

Feel free to show us how your Estradiol Molecule turned out!


Comment and share pictures below!

Tune in next week for another Molecule of the week!

See you then xoxo :)

 

Duluth Labs

Afton Direct LLC


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