Aspirin (Acetylsalicyclic Acid)

aspirin

Aspirin: Your Heart’s Best friend

Aspirin, very much like salicylic acid, only that it contains an acetyl (or ester group) instead of a hydroxyl group, hence, its other name, acetylsalicylic acid (ASA). It is commonly used for pain, inflammation (swelling) and fever. Moreover, it is also useful in preventing blood clot formation in patients with stroke, as well as heart attacks in high-risk hypertensive patients. Due to its blood thinning properties, it is not advised to be given as a pain reliever in patients with hemorrhage and dengue fever, as it may worsen such effects. It should be also given with caution in children and teenagers as it can cause serious liver and brain damage. Other than those precautions, aspirin is a great friend to the heart! 

What does Aspirin look like in Chemistry?

aspirin molecular structure
aspirin molecular structure

Let’s Get Building!

Using your Student Molecular Set from Duluth Labs let’s create Aspirin! You’ll need:

  • 9 Carbon Atoms

  • 4 Oxygen atoms

  • 8 Hydrogen atoms

  • 8 Small connectors (compact small bonds for hydrogen)

  • 8 Medium Connectors

  • 10 Long connectors

  • Molecular Tool (for Disassembly)

Put aside all the atoms and connectors needed.

Let’s Start Building With Our Benzene Portion !

aspirin molecular structure

Note: Let’s begin with Carbon 6! We start building this portion of the molecule in a clockwise direction.

Let’s start!

Steps:

  • 1
    aspirin molecular model

    1.Get one carbon atom (Carbon 6) then attach another carbon atom (Carbon 1) to it using 2 long connectors. Add a hydrogen atom on carbon 6 using a small connector.

  • 2
    aspirin molecular model

    2.Attach another carbon (Carbon 2) below Carbon 1 using a medium connector.

  • 3
    aspirin molecular model

    3.Then, get another carbon (Carbon 3) and attach this to Carbon 2 using 2 long connectors. Add a hydrogen atom to Carbon 3 using a small connector.

  • 4
    aspirin molecular model

    4.Add another carbon atom (Carbon 4) then attach this to Carbon 3 using a medium connector. Place a hydrogen atom on carbon 4 using a small connector.

  • 5
    aspirin molecular model

    5.Get another carbon atom (Carbon 5) then attach this to Carbon 4 using 2 long connectors. Add one hydrogen atom to carbon 5 using a small connector.

  • 6
    dopamine molecular model

    6.Join Carbon 5 and Carbon 6 together using a medium connector.

  • dopamine molecular model

    Yay! We've just built our Benzene Portion!

Note: Let’s now add the carboxylic acid functional group to our benzene ring, starting with the carbonyl carbon.

aspirin molecular structure

Steps:

  • 1
    dopamine molecular model

    1.Get one Carbon atom (Carbonyl Carbon) then attach this to Carbon 1 of the benzene portion using a medium connector. This is now the carbonyl carbon.

  • 2
    dopamine molecular model

    2.Add an Oxygen atom on this carbonyl carbon using 2 long connectors.

  • 3
    dopamine molecular model

    3.Add another oxygen atom on the carbonyl carbon using a medium connector. Then, add a hydrogen atom to this oxygen using a small connector

  • 4
    dopamine molecular model

    Yay! We've just built our Benzoic acid Portion!

Note: Let’s now add the ester functional group to our benzoic acid starting with the carbonyl carbon.

aspirin molecular structure

Steps:

  • 1
    dopamine molecular model

    1.Get one Oxygen atom then attach this to Carbon 2 (of the benzene portion) using a medium connector.

  • 2
    dopamine molecular model

    2.Add a carbon atom on this oxygen using 1 medium connector. This is now the carbonyl carbon.

  • 3
    dopamine molecular model

    3.Add another oxygen atom on the carbonyl carbon using 2 long connectors.

  • 4
    dopamine molecular model

    4.Finally, attach another carbon atom on the carbonyl carbon using a medium connector. Then, add 3 hydrogens to this carbon using 3 short connectors.

Great work! Now we have our newly-built Aspirin.

Feel free to show us how your Aspirin molecule turned out!


Comment and share pictures below!

Tune in next week for another Molecule of the week!

See you then xoxo :)

 

Duluth Labs

Afton Direct LLC


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  • irorzubglx on

    Muchas gracias. ?Como puedo iniciar sesion?


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